Synthesis of N-Benzenesulfonyl-p-Coumaramide from p-Coumaric Acid

Nasriadi Dali Wela, Arniah Dali Wela

Abstract


Abstrak: N-Benzenasulfonil-p-kumaramida telah disintesis dari asam p-kumarat. Penelitian ini bertujuan untuk mensintesis senyawa N-benzenasulfonil-p-kumaramida dari asam p-kumarat. Senyawa target N-benzenasulfonil-p-kumaramida diperoleh melalui dua tahap reaksi sintesis, yaitu tahap reaksi asilasi dan amidasi. Senyawa produk sintesis diidentifikasi dan dikarakterisasi dengan titik leleh, uji KLT, spektrometer FTIR, 1H-NMR, dan 13C-NMR. Hasil penelitian menunjukkan bahwa senyawa N-benzenasulfonil-p-kumaramida yang diperoleh berbentuk padatan putih (rendemen 78,57%) dengan titik leleh 145-147 oC dan KLT (SiO2, n-heksana : kloroform = 6 : 4 v/v, Rf = 0.45).

Keywords


Keywords: acylation, amidation, coumaramide, N-benzenesulfonyl-p-coumaramide, p-coumaric acid

References


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DOI: https://doi.org/10.24252/al-kimia.v6i2.5891

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