Steroid dari Kulit Batang Aglaia grandis (Meliaceae)

  • Kindi Farabi Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
    (ID)
  • Nurlelasari Nurlelasari Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
    (ID)
  • Siti Hani Pratiwi Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
    (ID)
  • Desi Harneti Universitas Padjajaran Bandung
    (ID)
  • Rani Maharani Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
  • Agus Safari Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
  • Unang Supratman Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia

Abstract

Steroids are a group of secondary metabolite which showed various biological activities. Meliaceae is a plant family used as a one of the source of steroid compounds. A. grandis is a member of the Meliaceae family in genus Aglaia which rarely explored. Previous studies have shown that A. grandis leaves contain triterpenoids, steroids, bisamide, and sesquiterpenoids. This study aims to obtain steroids from the bark of A. grandis. The structure of the isolated compound was determined using the NMR 1D and 2 D spectroscopic. Based on the extensive analysis, isolated compound identified as a stigmastant type steroid, stigmast-5-en-3β-ol-7-one.

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Author Biographies

Kindi Farabi, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
Department of Chemistry, Faculty of Mathematics and Natural Sciences,  Universitas Padjadjaran, Jatinangor 45363, Indonesia
Nurlelasari Nurlelasari, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
Department of Chemistry, Faculty of Mathematics and Natural Sciences,  Universitas Padjadjaran, Jatinangor 45363, Indonesia
Siti Hani Pratiwi, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
Department of Chemistry, Faculty of Mathematics and Natural Sciences,  Universitas Padjadjaran, Jatinangor 45363, Indonesia
Desi Harneti, Universitas Padjajaran Bandung

Nama Lengkap                        : Dr. Desi Harneti Putri Huspa

Tempat dan Tanggal Lahir      : Bandung, 11 April 1974

Nomor Telepon/Faks/ HP       : 022-87523459 /  085759209848

Alamat Kantor                                    : Jl. Raya Bandung-Sumedang KM-21 Jatinangor

Kabupaten Sumedang

e-mail                                      : desi.harneti@unpad.ac.id dan d_harneti@yahoo.com

 

Riwayat Pendidikan

S1                                            : Jurusan Kimia FMIPA UNPAD

S2                                            : Prodi Kimia Institut Teknologi Bandung

S3                                            : Prodi Kimia FMIPA UNPAD

 

Penelitian

Potensi Tumbuhan Toona Sureni Dan Chisocheton Macrophyllus Sebagai Obat Malaria

Synthesis Of Aureobasidin Analogues For New Aureobasidin Analogues

Senyawa Antikanker Payudara dari Tumbuhan Chisocheton

Senyawa Bioaktif dari Tumbuhan Indonesia dan Pemanfaatannya di Bidang Kesehatan dan Pertanian

Potensi  Mikroorganisme Dan Ekstrak Beberapa Tanaman Sebagai  Antimikroba  Dan Anti Kanker

Senyawa Antikanker Serviks dari Tumbuhan Meliaceae Indonesia Tahun ke-3

Senyawa Antikanker Serviks dari Tumbuhan Meliaceae Indonesia Tahun ke-2

Synthesis Of Aureobasidin Analogues For New Aureobasidin Analogues

Senyawa Antikanker Serviks dari Tumbuhan Meliaceae Indonesia Tahun Ke 1

Biologically Active Compounds from Indonesians Aglaia Plants

Senyawa Antimalaria dari Chisocheton macrophyllus Tahun ke-2

Triterpenoid yang Bersifat Antimalaria dari Tumbuhan Meliaceae Indonesia

 

Artikel Ilmiah

New Cytotoxic Pregnane-type Steroid from the Stem Bark of Aglaia elliptica (Meliaceae) :

Kindi Farabi 1 , Desi Harneti 1 , Nurlelasari 1 , Rani Maharani 1 , Ace Tatang Hidayat 1,2, Khalijah Awang 3 , Unang Supratman 1,2,* and Yoshihito Shiono 4

Rec. Nat. Prod. 12:2 (2018) 121-127

 

Cytotoxic Steroids from the Bark of Aglaia argentea (Meliaceae) :

Kindi Farabi1, Desi Harneti1, Nurlelasari1, Rani Maharani1,2,

Ace Tatang Hidayat1,2, Unang Supratman1,2*,

Khalijah Awang3 and Yoshihito Shiono4

CMU J. Nat. Sci. (2017) Vol. 16(4) 293

 

Activity of Cytotoxic Flavanoids against a P-388 Murine Leukemia Cell Line from the Stem Bark of Aglaia elliptica (Meliaceae) :

Ace Tatang Hidayat1,2, Kindi Farabi1 , Desi Harneti1 , Rani Maharani1,2 , Nurlelasari1 , Unang Supratman1,2*, and Yoshihito Shiono3

21/4 (2017), 163-168 doi: 10.7454/mss.v21i4.8836

 

Rani Maharani, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
Department of Chemistry, Faculty of Mathematics and Natural Sciences,  Universitas Padjadjaran, Jatinangor 45363, Indonesia
Agus Safari, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
Department of Chemistry, Faculty of Mathematics and Natural Sciences,  Universitas Padjadjaran, Jatinangor 45363, Indonesia
Unang Supratman, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Jatinangor 45363, Indonesia
Department of Chemistry, Faculty of Mathematics and Natural Sciences,  Universitas Padjadjaran, Jatinangor 45363, Indonesia

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Published
2021-06-21
How to Cite
Farabi, K., Nurlelasari, N., Pratiwi, S. H., Harneti, D., Maharani, R., Safari, A., & Supratman, U. (2021). Steroid dari Kulit Batang Aglaia grandis (Meliaceae). Al-Kimia, 9(1), 44-49. https://doi.org/10.24252/al-kimia.v9i1.17936
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Article
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