Antimicrobial Nanocomposite Materials Based Starch and Silver Nanoparticles

  • Ina Ristian STIKES Cendekia Utama


Starchs are matrix polimer with stabilization function for nanocomposite. The present study was to investigate antimicrobial activity of nanocomposite material from metal nanoparticles such as silver and matrix polimer. Silver nanoparticles (AgNPs) were succesfully synthesized by chemical reduction silver ion with  trisodium citrate as reducing agent. AgNPs were Characterized by spectrofotometre UV-Vis and transmission electron microscope (TEM). Stability of nanocomposite starch/AgNPs was analized by differential scanning calorimetry (DSC). Nanocomposite starch and AgNPs (starch/AgNPs) were prepared by simple mixing with in-situ blending. Characterization of AgNPs using TEM shows that the synthesized particles have a size less than 50 nm. Starch/AgNPs nanocomposite has proven to reduce bacteria e. Coli is up to 98% and has good thermal stability. Antimicrobial nanocomposites based natural polimer are new potential materials for biomedical.


Download data is not yet available.

Author Biography

Ina Ristian, STIKES Cendekia Utama
Program Studi Farmasi


Brown, P.K., Qureshi, A.T., Moll, A.N., Hayes, D.J., and Monroe, W.T. (2013). Silver Nanoscale Antisense Drug Delivery System for Photoactivated Gene Silencing. ACS Nano 7, 2948–2959.

Cheviron, P., Gouanvé, F., and Espuche, E. (2015). Starch/silver nanocomposite: Effect of thermal treatment temperature on the morphology, oxygen and water transport properties. Carbohydr. Polym. 134, 635–645.

Cheviron, P., Gouanvé, F., and Espuche, E. (2016). Preparation, characterization and barrier properties of silver/montmorillonite/starch nanocomposite films. J. Membr. Sci. 497, 162–171.

Folarin, O.M., Sadiku, E.R., and Maity, A. (2011). Polymer-noble metal nanocomposites.

Goyal, R., Macri, L.K., Kaplan, H.M., and Kohn, J. (2016). Nanoparticles and nanofibers for topical drug delivery. J. Controlled Release 240, 77–92.

Kanmani, P., and Rhim, J.-W. (2014a). Physicochemical properties of gelatin/silver nanoparticle antimicrobial composite films. Food Chem. 148, 162–169.

Kanmani, P., and Rhim, J.-W. (2014b). Physicochemical properties of gelatin/silver nanoparticle antimicrobial composite films. Food Chem. 148, 162–169.

Lu, D.R., Xiao, C.M., and Xu, S.J. (2009). Starch-based completely biodegradable polymer materials. Express Polym. Lett. 3, 366–375.

Maity, D., Mollick, M.M.R., Mondal, D., Bhowmick, B., Bain, M.K., Bankura, K., Sarkar, J., Acharya, K., and Chattopadhyay, D. (2012). Synthesis of methylcellulose?silver nanocomposite and investigation of mechanical and antimicrobial properties. Carbohydr. Polym. 90, 1818–1825.

Maneewattanapinyo, P., Banlunara, W., Thammacharoen, C., Ekgasit, S., and Kaewamatawong, T. (2011). An evaluation of acute toxicity of colloidal silver nanoparticles. J. Vet. Med. Sci. 73, 1417–1423.

Montazer, M., Hajimirzababa, H., Rahimi, M.K., and Alibakhshi, S. (2012). Durable anti-bacterial nylon carpet using colloidal nano silver. Fibres Text. East. Eur.

Mukkavalli, S., Chalivendra, V., and Singh, B.R. (2017). Physico-chemical analysis of herbally prepared silver nanoparticles and its potential as a drug bioenhancer. OpenNano 2, 19–27.

Rai, M., Ingle, A.P., Gupta, I., and Brandelli, A. (2015). Bioactivity of noble metal nanoparticles decorated with biopolymers and their application in drug delivery. Int. J. Pharm. 496, 159–172.

Rhim, J.W., Wang, L.F., and Hong, S.I. (2013). Preparation and characterization of agar/silver nanoparticles composite films with antimicrobial activity. Food Hydrocoll. 33, 327–335.

Satarkar, N., and Hilt, J. (2008). Magnetic hydrogel nanocomposites for remote controlled pulsatile drug release. J. Controlled Release 130, 246–251.

Yadollahi, M., Farhoudian, S., and Namazi, H. (2015). One-pot synthesis of antibacterial chitosan/silver bio-nanocomposite hydrogel beads as drug delivery systems. Int. J. Biol. Macromol. 79, 37–43.

Yoksan, R., and Chirachanchai, S. (2010). Silver nanoparticle-loaded chitosan?starch based films: Fabrication and evaluation of tensile, barrier and antimicrobial properties. Mater. Sci. Eng. C 30, 891–897.

Zhang, J., and Wang, Z.-W. (2013). Soluble dietary fiber from Canna edulis Ker by-product and its physicochemical properties. Carbohydr. Polym. 92, 289–296.

Zhang, J., Wang, Q., and Wang, A. (2010). In situ generation of sodium alginate/hydroxyapatite nanocomposite beads as drug-controlled release matrices. Acta Biomater. 6, 445–454.

Zhong, Q.-P., and Xia, W.-S. (2008). Physicochemical properties of edible and preservative films from chitosan/cassava starch/gelatin blend plasticized with glycerol. Food Technol. Biotechnol. 46, 262–269.

How to Cite
Ristian, I. (2019). Antimicrobial Nanocomposite Materials Based Starch and Silver Nanoparticles. Al-Kimia, 7(1), 39-45.
Abstract viewed = 572 times