IDENTIFIKASI EKSTRAK DAUN KOPASANDA (Chromolaena odorata Linn) TERHADAP SEL ANTIPROLIFERASI TIKUS LEUKEMIA L1210
DOI:
https://doi.org/10.24252/jfuinam.v4i3.2232Abstract
The anticancer activity of the extract kopasanda leaf against leukemia cells L1210. Simplicial kopasanda leaves extracted by maceration terraced with solvent n-heksan, etil asetat, etanol, and water. Test antiproliferative activity against leukemia cells L1210 to the extract in an instant four vitro indicate that IC50 extract respectively 9,2982 μg/mL (etil asetat), 11,3397 μg/mL air, 13,6176 μg/mL (etanol), and 14,1645 μg/mL (n-heksan).References
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[2] Anderson, R. N. Deaths: Leading Causes for 1999. National Vital Statistics Reports.
[3] Benjamin, VT. Phytochemical and Antibacterial Studies on The Essential Oil of Euphatorium Odoratum. Pharmaceutical Biology. 2011
Kimball, J. W. Biologi. Terjemahan oleh Hj. Siti SoetarmiTjitrosoepomo dan Nawangsari Sugiri. Jakarta: Erlangga. 1983.
[4] Mans DR, Rocha AB, Schwartsmann G. Anti-cancer drug discovery and development in Brazil: Targeted plant collection as a rational strategy to acquire candidate anti-cancer compounds, Oncologist 2000; 5, 185-198
[5] Ngozi, Igboh M., Jude, Ikewuchi C. and Catherine, Ikewuchi C. Chemical Profile of Chromolaena odorata L. (King and Robinson) Leaves.Pakistan Journal of Nutrition 8, 2009.
[6] Prawiradiputra, Bambang R. 2007. Ki Rinyuh (Chromolaena odorata (L.) R. M. King & H. Robinson): Gulma Padang Rumput Yang Merugikan. Bogor: Balai Penelitian Ternak.
[7] Sipayung, A., R.D. De Chenon And P.S. Sudharto. Observations on Chromolaena odorata (L.)R.M. King and H. Robinson in Indonesia. Second International Workshop on the Biological Control and Management of Chromolaena odorata. Biotrop, Bogor. 1991.
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[9] Thamrin, M. dan Asikin, S., Potensi gulma rawa sebagai bahan attraktan terhadap penggerek bantang padi putih (Scirpophaga innotata).Prosiding Seminar Nasional XVIII.Himpunan Ilmu Gulma Indonesia dan Fakultas Pertanian Universitas Mulawarman. 2007
[10] Winarno H dan Katrin E. aktivitas sitotoksik fraksi-fraksi ekstrak etil asetat kulit batang mahkota dewa (Phaleria macrocarpa (Scheff.)Boerl) terhadap sel aknker manusia. Majalah Obat Tradisional 2008; 13 (45) hal 120-127
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2017-02-25
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