• Ahyar Nur Akademi Keperawatan Anging Mammiri Provinsi Sulawesi Selatan
  • Kadek Ayu Erika
  • Andi Wardihan Sinrang Fakultas Kedokteran, Universitas Hasanuddin


Restless legs syndrome (RLS) is a common sensorimotor disorder in patients with chronic renal failure who undergo hemodialysis (HD). Pharmacological therapy is the main choice of RLS treatment that is at risk of side effects. Physical optimization of HD patients through stretching exercise is considered potentially effective in treating restless legs syndrome. This study aimed to identify the effect of stretching exercise on RLS in patients with chronic renal failure who underwent HD at Hasanuddin University Hospital. This research method used quasi experiment with pre- and post-test with control group design. The subjects in this study were 20 HD patients divided into two groups: 10 patients, Intervention and 10 control patients. Stretching exercise is given twice a week during the hemodialysis process, for 4 weeks. The RLS scale is measured using IRLS Scale. The collected data were then analyzed using the Wilcoxon test. The results showed that the respondents who received stretching exercise intervention experienced a decreaseof the RLS scale more significantly than the control group with ρ = 0.001 (ρ <0.05). This showed that there is a stretching exercise effect on the decrease of RLS scale. Therefore, stretching exercise could be made as one of the intervention treatment in which can be used to treat the patients with chronic renal failure and experienced RLS.


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Aliasgharpour, M., Abbasi, Z., Razi, S.P & Kazemnezhad, A. 2016. The effect of stretching exercises on severity of restless legs syndrome in patients on hemodialysis. Asian J Sports Med. 7 (2). doi: 10.5812/asjsm.31001.

Australia and New Zealand Dialysis and Transplant Registry. 2015. The 38th annual ANZDATA report. Retrived from

Black, J. M & Hawks, J. H. 2014. Keperawatan medikal bedah. Edisi 8. Buku 2. Singapore: Elsevier.

Cheema, B. S., O’Sullivan. J, Chan, M., Patwardhan A., Kelly, J., Gillin, A., Fiatarone S.M.A. 2006. Progressive resistance training during hemodialysis : rationale and method of a randomized-controlled trial. Hemodialysis International Journal. doi: 10.1111/j.1542-4758.2006.00112.x.

Christoforos, D.G., Georgios, M.H., Christina, K., Maria, D.M., Yiannis K., Paraskevi, F., ..., Ioannis, S. 2010. A single-blind randomized controlled trial to evaluate the effect of 6 months of progressive aerobic exercise training in patients with uraemic restless legs syndrome. ASAIO Journal, 56, 538–542. DOI: 10.1097/MAT.0b013e3181f1cc04

Ekbom, K., & Ulfberg, J. 2009. Restless legs syndrome. Journal of Internal Medicine, 266; 419–431. doi: 10.1111/j.1365-2796.2009.02159.x

Giannaki, C.D., Sakkas, G.K., Hadjigeorgiou, G.M., Karatzaferi, K., Patramani, G., & Lavdas, E. 2010. Non-pharmacological management of periodic limb movements during hemodialysis session in patients with uremic restless legs syndrome. ASAIO Journal, 56, 538–542

Gilman, E.A., Feely, M.A., Hildebrandt, D., Varayil, J.E., Chong, E.Y., Williams, A.W., Mueller, P.S. 2017. Do patients receiving hemodialysis regret starting dialysis? A survey of affected patients. Clinical Nephrology, Vol 87,117-123. doi 10.5414/CN109030.

Graef, P., Michaelsen, S.M., Dadalt, M.L.R., Rodrigues, D.A.M.S., & Pereira, F. 2014. Effects of functional and analytical strength training on upper-extremity activity after stroke: A randomized controlled trial. Braz J Phys Ther,1–3

Griffin,L., Cafarelli, E. 2005. Resistence training: cortical, spinal and motor unit adaptation. Can.J.Appl.Phsiol. 30(3):328-340

Heiwe, S., Jacobson S.H. 2011. Exercise training for adults with chronic kidney disease. Cochrane Database Syst Rev;10:CD003236

Hidayati, W. 2009. Laporan analisis praktek residensi spesialis keperawatan medikal bedah peminatan sistem perkemihan di RSUPN Dr. Cipto Mangunkusumo dan RS PGI Cikini, tidak dipublikasikan.

Hosseini, H., Kazemi, M., Azimpour. 2016. The effect of vibration on the severity of restless legs syndrome in hemodialysis patients. Journal of Renal Injury Prevention. 6(2): 113-116. doi: 10.15171/jrip.2017.22.

Indonesian Renal Registry. 2015. 8th report of Indonesian renal registry. Retrived from.

K/DOQI Workgroup. 2005. K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis.;45: S1–S153.

Kaur , J., Venkateasan, M., Kaur, K., Rawat, P.S., Massey, H. 2016. Effectiveness of muscle stretching exercise on quality of life of haemodialysis patients. International Journal of Medical Research & Health Sciences, 5, 4:203-207. ISSN No: 2319-5886

Klingelhoefer, L., Bhattacharya, K., Reichmann, H., 2016. Restless legs syndrome. Clin Med. 16:379-82. doi: 10.7861/ clinmedicine.16-4-379.

Lazano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, ..., Adair, I. 2012. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden.

Mahrova A., Svagrova K. 2013. Exercise Therapy–Additional Tool for Managing Physical and Psychological Problems on Hemodialysis. In: Suzuki H, editor. Hemodialysis. InTech.

Morishita, Y., Nagata, D. 2015. Strategies to improve physical activity by exercise training in patiens with chonic kidney disease. International Journal Of Neprology And Renovascular Disease. 8:19-24.

Mortazavi, M.,Vahdatpour, B.,Ghasempour, A.,Taheri, D., Shahidi, S., & Moeinzadeh, F. 2013. Aerobic exercise improves signs of restless leg syndrome in end stage renal disease patients suffering chronic hemodialysis. The Scientific World Journal,1–4.

National Kidney Foundation. 2015. KDOQI clinical practice guideline for hemodialysis adequacy: 2015 update. Am J Kidney. 66(5):884-930.

-----------------. 2012. KDOQI clinical practice guideline for diabetes and CKD: 2012 update. Am J Kidney. 60(5):850-886.

LeMone, P., Burke, K. 2008. Medical surgical nursing critical thinking in care. New Jearsey : Pearson.

Lin Z., Zhao,C., Luo, Q., Xia, X., Yu, X., & Huang, F. 2016. Prevalence of restless legs syndrome in chronic kidney disease: a systematic review and meta analysis of observational studies. Renal Failure J.

Ohayon MM, Roth T. 2002. Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. J Psychosom Res. 53(1):547–54.

Painter, P. 2000. A guide for people on dialysis. Rehabilitation Resource Center: Medical Education Institute, Inc.

Parsons, T.K., Tosselmire E.D., King-VanVlack, C.E. 2006. Exercise training during hemodialysis improves dyalisis efficacy and physical performance. Exercise Arch phys med rehabil, 87(5):680-7.doi : 10.1016/j.apmr.2005.12.044.

Sakkas GK, Hadjigeorgiou GM, Karatzaferi C, Maridaki MD, Giannaki CD, Mertens PR. (2008) .Intradialytic aerobic exercise training ameliorates symptoms of restless legs syndrome and improves functional capacity in patients on hemodialysis: a pilot study. ASAIO J 54(2):185–90. doi: 10.1097/MAT.0b013e3181641b07.

Seifer, T., Brassard, P., Wissenberg, M., Rasmussen, P., Nordby, P., Stallknecht, B., ..., Secher, N.H. 2010. Endurance training enhances BDNF release from the human brain. Am J Physiol Regul Integr Comp Physiol, 298, R372–R377.

Shahgholian, N., Ghafourifard, M., Rafieian,M., & Mortazavi, M. 2008. Impact of two types of sodium and ultrafiltration profiles on intradialytic hypotension in hemodialysis patients. IJNMR Autumn. 13, 135-136.

Shahgholian, N., Jazi, S.K., Karimian, J., Valiani, M. 2015. The effects of two methods of reflexology and stretching exercises on the severity of restless leg syndrome among hemodialysis patients. Iranian Journal of Nursing and Midwifery Research, 21:219-24. doi : 10.4103/1735-9066.180381.

Sherwood, L. 2014. Fisiologi manusia : dari sel ke sistem. Edisi 8. Jakarta: EGC

Smart, N., & Stelee, M. 2011. Exercise training in haemodialysis patients: A systematic review and meta-analysis. Nephrology, 16, 626–632. doi:10.1111/j.1440-1797.2011.01471.x

Smeltzer, S.C., & Bare. B.G. 2009. Buku ajar keperawatan medikal bedah brunner &. suddarth ( Edisi 8 Volume 1). Philladelphia: Lipincott Williams & Wilknis.

United State Renal Data System. 2015. USRDS annual data report volume 2: ESRD in the United States. Retrived from

How to Cite
Nur, A., Erika, K. A., & Sinrang, A. W. (2018). THE EFFECT OF INTRADIALYSIS STRETCHING EXERCISE ON THE SCALE OF RESTLESS LEG SYNDROME. Journal of Islamic Nursing, 3(2), 16-24.
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