Baccaurea lanceolata Pericarpium as a Potential Natural Antibacterial Agent Against Staphylococcus epidermidis

Authors

  • Irfan Zamzani Universitas Muhammadiyah Banjarmasin
  • Triadisti Universitas Muhammadiyah Banjarmasin
  • Nor Latifah Universitas Muhammadiyah Banjarmasin
  • Sri Rahayu Universitas Muhammadiyah Banjarmasin

DOI:

https://doi.org/10.24252/djps.v9i1.59586

Keywords:

Baccaurea lanceolata, pericarpium, antibacterial, S. epidermidis, phenol and flavonoid content

Abstract

Introduction: Natural plant-based compounds have gained increasing attention as alternative antibacterial agents, particularly in response to rising antibiotic resistance. Aims: This study aimed to assess the antibacterial activity of limpasu (Baccaurea lanceolata) pericarpium extracts against S. epidermidis and to relate their effectiveness to flavonoid and phenolic contents. Result: The antibacterial activity and phytochemical composition of limpasu pericarp extracts were evaluated against S. epidermidis. Extracts were prepared using solvents of varying polarities: n-hexane, ethyl acetate (EtOAc), and methanol (MeOH). Antibacterial activity was assessed via the disc diffusion method at concentrations of 10%, 20%, 40%, and 80%. The EtOAc extract exhibited the strongest inhibitory effect, with inhibition zones increasing dose-dependently, reaching up to 24.33±1.63 mm at 80%. The n-hexane extract showed the least antibacterial activity, whereas MeOH extract exhibited moderate inhibition. Phytochemical analysis revealed that the EtOAc extract had the highest total flavonoid content (29.16 ± 0.49 mg quercetin/g extract) and total phenolic content (2.12 ± 0.11 mg GAE/g extract), correlating with its superior bioactivity.  Conclusion: These findings suggest that limpasu pericarpium, particularly its EtOAc extract, holds promise as a natural antibacterial agent against S. epidermidis, possibly due to its high phenolic and flavonoid contents

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Published

2026-06-30

How to Cite

Zamzani, I., Triadisti, N., Latifah, N., & Rahayu, S. (2026). Baccaurea lanceolata Pericarpium as a Potential Natural Antibacterial Agent Against Staphylococcus epidermidis. Ad-Dawaa’ Journal of Pharmaceutical Sciences, 9(1), 25–34. https://doi.org/10.24252/djps.v9i1.59586

Issue

Vol.9 No. 1 (2026)

Section

Artikel

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Copyright (c) 2026 Irfan Zamzani, Triadisti, Nor Latifah, Sri Rahayu

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